7P7G

Crystal structure of phosphorylated pT220 Casein Kinase I delta (CK1d), conformation 2 and 3

7P7G の概要

• エントリーDOI: 10.2210/pdb7p7g/pdb
• 分子名称: Casein kinase I isoform delta, CITRIC ACID, 1,2-ETHANEDIOL, ... (5 entities in total)
• 機能のキーワード: casein kinase, ck1d, csnk1d, conformation plasticity, alpha g, activation segment, phosphorylation., structural genomics, structural genomics consortium, sgc, transferase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 70590.72

構造登録者

Chaikuad, A.,Zhubi, R.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2021-07-19, 公開日: 2022-04-13, 最終更新日: 2024-01-31)

• 主引用文献: Cullati, S.N.,Chaikuad, A.,Chen, J.S.,Gebel, J.,Tesmer, L.,Zhubi, R.,Navarrete-Perea, J.,Guillen, R.X.,Gygi, S.P.,Hummer, G.,Dotsch, V.,Knapp, S.,Gould, K.L.; Kinase domain autophosphorylation rewires the activity and substrate specificity of CK1 enzymes.; Mol.Cell, 82:2006-, 2022; PubMed: 35353987; DOI: 10.1016/j.molcel.2022.03.005

実験手法

X-RAY DIFFRACTION (1.7 Å)