7P4D
Crystal Structure of Agd31B, alpha-transglucosylase in Glycoside Hydrolase Family 31, in complex with covalent Cyclophellitol Sulfamidate probe KK130
This is a non-PDB format compatible entry.
Summary for 7P4D
| Entry DOI | 10.2210/pdb7p4d/pdb |
| Related | 7P2Z 7P32 7P4C |
| Descriptor | Oligosaccharide 4-alpha-D-glucosyltransferase, 1,2-ETHANEDIOL, TETRAETHYLENE GLYCOL, ... (7 entities in total) |
| Functional Keywords | glycoside hydrolase, gh31, inhibitor, carbohydrate, hydrolase |
| Biological source | Cellvibrio japonicus (strain Ueda107) (Pseudomonas fluorescens subsp. cellulosa) |
| Total number of polymer chains | 1 |
| Total formula weight | 96024.85 |
| Authors | Wu, L.,Davies, G.J. (deposition date: 2021-07-11, release date: 2022-07-27, Last modification date: 2024-01-31) |
| Primary citation | Kok, K.,Kuo, C.L.,Katzy, R.E.,Lelieveld, L.T.,Wu, L.,Roig-Zamboni, V.,van der Marel, G.A.,Codee, J.D.C.,Sulzenbacher, G.,Davies, G.J.,Overkleeft, H.S.,Aerts, J.M.F.G.,Artola, M. 1,6- epi-Cyclophellitol Cyclosulfamidate Is a Bona Fide Lysosomal alpha-Glucosidase Stabilizer for the Treatment of Pompe Disease. J.Am.Chem.Soc., 144:14819-14827, 2022 Cited by PubMed: 35917590DOI: 10.1021/jacs.2c05666 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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