7P0W
Crystal structure of a trapped Pab-AGOG/double-standed DNA covalent intermediate (DNA containing thymine opposite to lesion)
Summary for 7P0W
Entry DOI | 10.2210/pdb7p0w/pdb |
Descriptor | N-glycosylase/DNA lyase, DNA (5'-D(*TP*TP*TP*(PED)P*TP*TP*TP*CP*T)-3'), DNA (5'-D(*AP*GP*AP*AP*AP*TP*AP*AP*A)-3'), ... (6 entities in total) |
Functional Keywords | 8-oxoguanine dna glycosylase, agog, pyrococcus abyssi, trapped double-stranded dna intermediate, hydrolase |
Biological source | Pyrococcus abyssi (strain GE5 / Orsay) More |
Total number of polymer chains | 3 |
Total formula weight | 33601.42 |
Authors | Coste, F.,Goffinont, S.,Flament, D.,Castaing, B. (deposition date: 2021-06-30, release date: 2022-07-13, Last modification date: 2024-01-31) |
Primary citation | Franck, C.,Stephane, G.,Julien, C.,Virginie, G.,Martine, G.,Norbert, G.,Fabrice, C.,Didier, F.,Josef, S.M.,Bertrand, C. Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing. Nucleic Acids Res., 50:11072-11092, 2022 Cited by PubMed: 36300625DOI: 10.1093/nar/gkac932 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.12 Å) |
Structure validation
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