7P0N
Crystal structure of L-Trp/Indoleamine 2,3-dioxygenagse 1 (hIDO1) complex with the JK-loop refined in the open conformation
Summary for 7P0N
Entry DOI | 10.2210/pdb7p0n/pdb |
Descriptor | Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, N'-Formylkynurenine, ... (9 entities in total) |
Functional Keywords | l-trp metabolism, hemoprotein, dynamics loop, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 187517.93 |
Authors | Mirgaux, M.,Wouters, J. (deposition date: 2021-06-30, release date: 2021-12-29, Last modification date: 2024-01-31) |
Primary citation | Mirgaux, M.,Leherte, L.,Wouters, J. Temporary Intermediates of L-Trp Along the Reaction Pathway of Human Indoleamine 2,3-Dioxygenase 1 and Identification of an Exo Site. Int J Tryptophan Res, 14:11786469211052964-11786469211052964, 2021 Cited by PubMed: 34949925DOI: 10.1177/11786469211052964 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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