7P0N

Crystal structure of L-Trp/Indoleamine 2,3-dioxygenagse 1 (hIDO1) complex with the JK-loop refined in the open conformation

7P0N の概要

• エントリーDOI: 10.2210/pdb7p0n/pdb
• 分子名称: Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, N'-Formylkynurenine, ... (9 entities in total)
• 機能のキーワード: l-trp metabolism, hemoprotein, dynamics loop, oxidoreductase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 187517.93

構造登録者

Mirgaux, M.,Wouters, J. (登録日: 2021-06-30, 公開日: 2021-12-29, 最終更新日: 2024-01-31)

• 主引用文献: Mirgaux, M.,Leherte, L.,Wouters, J.; Temporary Intermediates of L-Trp Along the Reaction Pathway of Human Indoleamine 2,3-Dioxygenase 1 and Identification of an Exo Site.; Int J Tryptophan Res, 14:11786469211052964-11786469211052964, 2021; PubMed: 34949925; DOI: 10.1177/11786469211052964

実験手法

X-RAY DIFFRACTION (2.5 Å)