7P0A

CRYSTAL STRUCTURE OF THE MURINE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX H-2DB IN COMPLEX WITH LCMV-DERIVED GP33 PEPTIDE with D-AMINOACID (p3P6f)

7P0A の概要

• エントリーDOI: 10.2210/pdb7p0a/pdb
• 分子名称: H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, Stable signal peptide, ... (6 entities in total)
• 機能のキーワード: d-aminoacid, class i major histocompatibility complex, b2-microglobulin, immune system
• 由来する生物種: Mus musculus (House Mouse); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 90694.33

構造登録者

Broggini, L.,Ricagno, S. (登録日: 2021-06-29, 公開日: 2022-03-23, 最終更新日: 2024-01-31)

• 主引用文献: Ballabio, F.,Broggini, L.,Paissoni, C.,Han, X.,Peqini, K.,Sala, B.M.,Sun, R.,Sandalova, T.,Barbiroli, A.,Achour, A.,Pellegrino, S.,Ricagno, S.,Camilloni, C.; l- to d-Amino Acid Substitution in the Immunodominant LCMV-Derived Epitope gp33 Highlights the Sensitivity of the TCR Recognition Mechanism for the MHC/Peptide Structure and Dynamics.; Acs Omega, 7:9622-9635, 2022; PubMed: 35350306; DOI: 10.1021/acsomega.1c06964

実験手法

X-RAY DIFFRACTION (2.429 Å)