7OW1
Crystal Structure of TAP01 in complex with amyloid beta peptide
Summary for 7OW1
Entry DOI | 10.2210/pdb7ow1/pdb |
Descriptor | Amyloid-beta precursor protein, TAP01 family antibody heavy chain, TAP01 family antibody light chain, ... (5 entities in total) |
Functional Keywords | alzheimer's disease, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 3 |
Total formula weight | 48446.81 |
Authors | Hall, G.,Cowan, R.,Carr, M.D. (deposition date: 2021-06-16, release date: 2022-06-29, Last modification date: 2024-01-31) |
Primary citation | Bakrania, P.,Hall, G.,Bouter, Y.,Bouter, C.,Beindorff, N.,Cowan, R.,Davies, S.,Price, J.,Mpamhanga, C.,Love, E.,Matthews, D.,Carr, M.D.,Bayer, T.A. Discovery of a novel pseudo beta-hairpin structure of N-truncated amyloid-beta for use as a vaccine against Alzheimer's disease. Mol Psychiatry, 27:840-848, 2022 Cited by PubMed: 34776512DOI: 10.1038/s41380-021-01385-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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