7OW1

Crystal Structure of TAP01 in complex with amyloid beta peptide

Summary for 7OW1

• Entry DOI: 10.2210/pdb7ow1/pdb
• Descriptor: Amyloid-beta precursor protein, TAP01 family antibody heavy chain, TAP01 family antibody light chain, ... (5 entities in total)
• Functional Keywords: alzheimer's disease, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 3
• Total formula weight: 48446.81

Authors

Hall, G.,Cowan, R.,Carr, M.D. (deposition date: 2021-06-16, release date: 2022-06-29, Last modification date: 2024-01-31)

• Primary citation: Bakrania, P.,Hall, G.,Bouter, Y.,Bouter, C.,Beindorff, N.,Cowan, R.,Davies, S.,Price, J.,Mpamhanga, C.,Love, E.,Matthews, D.,Carr, M.D.,Bayer, T.A.; Discovery of a novel pseudo beta-hairpin structure of N-truncated amyloid-beta for use as a vaccine against Alzheimer's disease.; Mol Psychiatry, 27:840-848, 2022; PubMed: 34776512; DOI: 10.1038/s41380-021-01385-7

Experimental method

X-RAY DIFFRACTION (1.4 Å)