7OW1

Crystal Structure of TAP01 in complex with amyloid beta peptide

7OW1 の概要

• エントリーDOI: 10.2210/pdb7ow1/pdb
• 分子名称: Amyloid-beta precursor protein, TAP01 family antibody heavy chain, TAP01 family antibody light chain, ... (5 entities in total)
• 機能のキーワード: alzheimer's disease, immune system
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 48446.81

構造登録者

Hall, G.,Cowan, R.,Carr, M.D. (登録日: 2021-06-16, 公開日: 2022-06-29, 最終更新日: 2024-01-31)

• 主引用文献: Bakrania, P.,Hall, G.,Bouter, Y.,Bouter, C.,Beindorff, N.,Cowan, R.,Davies, S.,Price, J.,Mpamhanga, C.,Love, E.,Matthews, D.,Carr, M.D.,Bayer, T.A.; Discovery of a novel pseudo beta-hairpin structure of N-truncated amyloid-beta for use as a vaccine against Alzheimer's disease.; Mol Psychiatry, 27:840-848, 2022; PubMed: 34776512; DOI: 10.1038/s41380-021-01385-7

実験手法

X-RAY DIFFRACTION (1.4 Å)