7OUK
BDM88855 inhibitor bound to the transmembrane domain of AcrB
Summary for 7OUK
Entry DOI | 10.2210/pdb7ouk/pdb |
Descriptor | Multidrug efflux pump subunit AcrB, (2S)-3-hydroxypropane-1,2-diyl didecanoate, DECYLAMINE-N,N-DIMETHYL-N-OXIDE, ... (14 entities in total) |
Functional Keywords | multidrug efflux pump, membrane protein, transport protein |
Biological source | Escherichia coli More |
Total number of polymer chains | 5 |
Total formula weight | 389723.24 |
Authors | Tam, H.K.,Foong, W.E.,Pos, K.M. (deposition date: 2021-06-12, release date: 2021-12-29, Last modification date: 2024-01-31) |
Primary citation | Ple, C.,Tam, H.K.,Vieira Da Cruz, A.,Compagne, N.,Jimenez-Castellanos, J.C.,Muller, R.T.,Pradel, E.,Foong, W.E.,Malloci, G.,Ballee, A.,Kirchner, M.A.,Moshfegh, P.,Herledan, A.,Herrmann, A.,Deprez, B.,Willand, N.,Vargiu, A.V.,Pos, K.M.,Flipo, M.,Hartkoorn, R.C. Pyridylpiperazine-based allosteric inhibitors of RND-type multidrug efflux pumps. Nat Commun, 13:115-115, 2022 Cited by PubMed: 35013254DOI: 10.1038/s41467-021-27726-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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