7ORU

Non-structural protein 10 (nsp10) from SARS CoV-2 in complex with fragment VT00221

7ORU の概要

• エントリーDOI: 10.2210/pdb7oru/pdb
• 分子名称: Non-structural protein 10, ZINC ION, DIMETHYL SULFOXIDE, ... (7 entities in total)
• 機能のキーワード: fragment, complex, small molecule, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 13878.49

構造登録者

Talibov, V.O.,Kozielski, F.,Sele, C.,Lou, J.,Dong, D.,Wang, Q.,Shi, X.,Nyblom, M.,Rogstam, A.,Krojer, T.,Knecht, W.,Fisher, S.Z. (登録日: 2021-06-06, 公開日: 2021-10-20, 最終更新日: 2024-01-31)

• 主引用文献: Kozielski, F.,Sele, C.,Talibov, V.O.,Lou, J.,Dong, D.,Wang, Q.,Shi, X.,Nyblom, M.,Rogstam, A.,Krojer, T.,Fisher, Z.,Knecht, W.; Identification of fragments binding to SARS-CoV-2 nsp10 reveals ligand-binding sites in conserved interfaces between nsp10 and nsp14/nsp16.; Rsc Chem Biol, 3:44-55, 2022; PubMed: 35128408; DOI: 10.1039/d1cb00135c

実験手法

X-RAY DIFFRACTION (1.67 Å)