7ORD
The crystal structure of the domain-swapped dimer of onconase (2)
This is a non-PDB format compatible entry.
Summary for 7ORD
Entry DOI | 10.2210/pdb7ord/pdb |
Descriptor | Protein P-30, ACETATE ION, SULFATE ION, ... (4 entities in total) |
Functional Keywords | ribonuclease; onconase; onconase dimer; 3d domain swapping; antitumor activity, hydrolase |
Biological source | Lithobates pipiens (Northern leopard frog, Rana pipiens) |
Total number of polymer chains | 2 |
Total formula weight | 24102.66 |
Authors | Merlino, A.,Loreto, D. (deposition date: 2021-06-05, release date: 2021-10-06, Last modification date: 2024-01-31) |
Primary citation | Gotte, G.,Campagnari, R.,Loreto, D.,Bettin, I.,Calzetti, F.,Menegazzi, M.,Merlino, A. The crystal structure of the domain-swapped dimer of onconase highlights some catalytic and antitumor activity features of the enzyme. Int.J.Biol.Macromol., 191:560-571, 2021 Cited by PubMed: 34563576DOI: 10.1016/j.ijbiomac.2021.09.095 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.14 Å) |
Structure validation
Download full validation report