7ORD

The crystal structure of the domain-swapped dimer of onconase (2)

This is a non-PDB format compatible entry.

Summary for 7ORD

• Entry DOI: 10.2210/pdb7ord/pdb
• Descriptor: Protein P-30, ACETATE ION, SULFATE ION, ... (4 entities in total)
• Functional Keywords: ribonuclease; onconase; onconase dimer; 3d domain swapping; antitumor activity, hydrolase
• Biological source: Lithobates pipiens (Northern leopard frog, Rana pipiens)
• Total number of polymer chains: 2
• Total formula weight: 24102.66

Authors

Merlino, A.,Loreto, D. (deposition date: 2021-06-05, release date: 2021-10-06, Last modification date: 2024-01-31)

• Primary citation: Gotte, G.,Campagnari, R.,Loreto, D.,Bettin, I.,Calzetti, F.,Menegazzi, M.,Merlino, A.; The crystal structure of the domain-swapped dimer of onconase highlights some catalytic and antitumor activity features of the enzyme.; Int.J.Biol.Macromol., 191:560-571, 2021; PubMed: 34563576; DOI: 10.1016/j.ijbiomac.2021.09.095

Experimental method

X-RAY DIFFRACTION (2.14 Å)