7ORC
Human Aldehyde Oxidase in complex with Raloxifene
Summary for 7ORC
Entry DOI | 10.2210/pdb7orc/pdb |
Related | 7OPN |
Descriptor | Aldehyde oxidase, FE2/S2 (INORGANIC) CLUSTER, PHOSPHONIC ACIDMONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,7,8A,9,10,10A-HEXAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL)ESTER, ... (8 entities in total) |
Functional Keywords | human aldehyde oxidase, complex, inhibitor, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 301882.62 |
Authors | Mota, C.,Coelho, C.,Santos Silva, T.,Romao, M.J. (deposition date: 2021-06-05, release date: 2021-09-01, Last modification date: 2024-01-31) |
Primary citation | Mota, C.,Diniz, A.,Coelho, C.,Santos-Silva, T.,Esmaeeli, M.,Leimkuhler, S.,Cabrita, E.J.,Marcelo, F.,Romao, M.J. Interrogating the Inhibition Mechanisms of Human Aldehyde Oxidase by X-ray Crystallography and NMR Spectroscopy: The Raloxifene Case. J.Med.Chem., 64:13025-13037, 2021 Cited by PubMed: 34415167DOI: 10.1021/acs.jmedchem.1c01125 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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