7OQ4

Cryo-EM structure of the ATV RNAP Inhibitory Protein (RIP) bound to the DNA-binding channel of the host's RNA polymerase

Summary for 7OQ4

• Entry DOI: 10.2210/pdb7oq4/pdb
• Related: 7OK0
• EMDB information: 13026
• Descriptor: DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit L, DNA-directed RNA polymerase subunit N, ... (17 entities in total)
• Functional Keywords: viral inhibitor, transcription inhibition, atv, archaeal virus, archaea, viral protein
• Biological source: Acidianus two-tailed virus (ATV); More
• Total number of polymer chains: 14
• Total formula weight: 423295.85

Authors

Pilotto, S.,Fouqueau, T.,Lukoyanova, N.,Sheppard, C.,Lucas-Staat, S.,Diaz-Santin, L.M.,Matelska, D.,Prangishvili, D.,Cheung, A.C.M.,Werner, F. (deposition date: 2021-06-02, release date: 2021-08-25, Last modification date: 2021-10-13)

• Primary citation: Pilotto, S.,Fouqueau, T.,Lukoyanova, N.,Sheppard, C.,Lucas-Staat, S.,Diaz-Santin, L.M.,Matelska, D.,Prangishvili, D.,Cheung, A.C.M.,Werner, F.; Structural basis of RNA polymerase inhibition by viral and host factors.; Nat Commun, 12:5523-5523, 2021; PubMed: 34535646; DOI: 10.1038/s41467-021-25666-5

Experimental method

ELECTRON MICROSCOPY (3.27 Å)