7OP7

Bacteroides thetaiotaomicron mannosidase GH2 with beta-manno-configured N-alkyl cyclophellitol aziridine

7OP7 の概要

• エントリーDOI: 10.2210/pdb7op7/pdb
• 分子名称: Beta-mannosidase, 1,2-ETHANEDIOL, (1R,2S,3R,4S,5R,6R)-5-(8-azidooctylamino)-6-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol, ... (6 entities in total)
• 機能のキーワード: mannosidase, cyclophellitol aziridine, hydrolase
• 由来する生物種: Bacteroides thetaiotaomicron VPI-5482
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 200657.91

構造登録者

McGregor, N.G.S.,Beenakker, T.J.M.,Kuo, C.,Wong, C.,Offen, W.A.,Armstrong, Z.,Codee, J.D.C.,Aerts, J.M.F.G.,Florea, B.I.,Overkleeft, H.S.,Davies, G.J. (登録日: 2021-05-29, 公開日: 2022-02-02, 最終更新日: 2024-01-31)

• 主引用文献: McGregor, N.G.S.,Kuo, C.L.,Beenakker, T.J.M.,Wong, C.S.,Offen, W.A.,Armstrong, Z.,Florea, B.I.,Codee, J.D.C.,Overkleeft, H.S.,Aerts, J.M.F.G.,Davies, G.J.; Synthesis of broad-specificity activity-based probes for exo -beta-mannosidases.; Org.Biomol.Chem., 20:877-886, 2022; PubMed: 35015006; DOI: 10.1039/d1ob02287c

実験手法

X-RAY DIFFRACTION (1.85 Å)