7OH4

Cryo-EM structure of Drs2p-Cdc50p in the E1 state with PI4P and Mg2+ bound

7OH4 の概要

• エントリーDOI: 10.2210/pdb7oh4/pdb
• EMDBエントリー: 12893 12894 12895 12896
• 分子名称: Probable phospholipid-transporting ATPase DRS2,Probable phospholipid-transporting ATPase DRS2, Cell division control protein 50, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: lipid flippase, p4 atpase, trans-golgi network, phosphatidylserine transport, membrane protein
• 由来する生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 214357.26

構造登録者

Timcenko, M.,Dieudonne, T.,Montigny, C.,Boesen, T.,Lyons, J.A.,Lenoir, G.,Nissen, P. (登録日: 2021-05-09, 公開日: 2021-06-09)

• 主引用文献: Timcenko, M.,Dieudonne, T.,Montigny, C.,Boesen, T.,Lyons, J.A.,Lenoir, G.,Nissen, P.; Structural basis of substrate-independent phosphorylation in a P4-ATPase lipid flippase; J.Mol.Biol., :167062-, 2021; PubMed: 34023399; DOI: 10.1016/j.jmb.2021.167062

実験手法

ELECTRON MICROSCOPY (3 Å)