7OCL

K1K1, a potent recombinant minimal hepatocyte growth factor/scatter factor mimic

7OCL の概要

• エントリーDOI: 10.2210/pdb7ocl/pdb
• 分子名称: Hepatocyte growth factor alpha chain,Hepatocyte growth factor alpha chain (2 entities in total)
• 機能のキーワード: met receptor agonist, hgf/sf kringle 1 dimer, hgf/sf-derived recombinant protein, met-activator, regeneration of epithelial tissue and organs, engineered growth factor, de novo protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 38465.31

構造登録者

de Jonge, H.,de Nola, G.,Gherardi, E. (登録日: 2021-04-27, 公開日: 2021-07-21, 最終更新日: 2024-05-01)

• 主引用文献: de Nola, G.,Leclercq, B.,Mougel, A.,Taront, S.,Simonneau, C.,Forneris, F.,Adriaenssens, E.,Drobecq, H.,Iamele, L.,Dubuquoy, L.,Melnyk, O.,Gherardi, E.,de Jonge, H.,Vicogne, J.; Dimerization of kringle 1 domain from hepatocyte growth factor/scatter factor provides a potent MET receptor agonist.; Life Sci Alliance, 5:-, 2022; PubMed: 35905995; DOI: 10.26508/lsa.202201424

実験手法

X-RAY DIFFRACTION (1.8 Å)