7OC7
LasB, alpha-alkyl-N-aryl mercaptoacetamide
Summary for 7OC7
Entry DOI | 10.2210/pdb7oc7/pdb |
Descriptor | Neutral metalloproteinase, ZINC ION, (2R)-N,3-diphenyl-2-sulfanyl-propanamide, ... (5 entities in total) |
Functional Keywords | lasb, alpha-alkyl-n-aryl mercaptoacetamide, hydrolase |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 1 |
Total formula weight | 33422.16 |
Authors | Koehnke, J.,Sikandar, A. (deposition date: 2021-04-26, release date: 2022-01-19, Last modification date: 2024-01-31) |
Primary citation | Kaya, C.,Walter, I.,Yahiaoui, S.,Sikandar, A.,Alhayek, A.,Konstantinovic, J.,Kany, A.M.,Haupenthal, J.,Kohnke, J.,Hartmann, R.W.,Hirsch, A.K.H. Substrate-Inspired Fragment Merging and Growing Affords Efficacious LasB Inhibitors. Angew.Chem.Int.Ed.Engl., 61:e202112295-e202112295, 2022 Cited by PubMed: 34762767DOI: 10.1002/anie.202112295 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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