7OC1
Structure of Pseudomonas aeruginosa FabF mutant C164Q in complex with Platensimycin
Summary for 7OC1
Entry DOI | 10.2210/pdb7oc1/pdb |
Descriptor | 3-oxoacyl-[acyl-carrier-protein] synthase 2, PLATENSIMYCIN, DIMETHYL SULFOXIDE, ... (6 entities in total) |
Functional Keywords | inhibitor, antibiotic, fatty acid biosynthesis pathway |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 2 |
Total formula weight | 88519.03 |
Authors | Georgiou, C.,Brenk, R.,Espeland, L.O.,Klein, R. (deposition date: 2021-04-25, release date: 2021-08-25, Last modification date: 2024-01-31) |
Primary citation | Espeland, L.O.,Georgiou, C.,Klein, R.,Bhukya, H.,Haug, B.E.,Underhaug, J.,Mainkar, P.S.,Brenk, R. An Experimental Toolbox for Structure-Based Hit Discovery for P. aeruginosa FabF, a Promising Target for Antibiotics. Chemmedchem, 16:2715-2726, 2021 Cited by PubMed: 34189850DOI: 10.1002/cmdc.202100302 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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