7OBH
Crystal structure of 14-3-3 sigma in complex with NPM1 phosphopeptide and stabilizer Fusicoccin-A
Summary for 7OBH
Entry DOI | 10.2210/pdb7obh/pdb |
Descriptor | 14-3-3 protein sigma, NPM1 phosphopeptide, FUSICOCCIN, ... (5 entities in total) |
Functional Keywords | 14-3-3 sigma protein-peptide-stabilizer complex, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 30497.48 |
Authors | Centorrino, F.,Andlovic, B.,Ottmann, C. (deposition date: 2021-04-22, release date: 2022-05-04, Last modification date: 2024-02-07) |
Primary citation | Andlovic, B.,Heilmann, G.,Ninck, S.,Andrei, S.A.,Centorrino, F.,Higuchi, Y.,Kato, N.,Brunsveld, L.,Arkin, M.,Menninger, S.,Choidas, A.,Wolf, A.,Klebl, B.,Kaschani, F.,Kaiser, M.,Eickhoff, J.,Ottmann, C. IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023 Cited by PubMed: 37130519DOI: 10.1016/j.chembiol.2023.04.005 PDB entries with the same primary citation |
Experimental method |
Structure validation
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