7OB4
Cryo-EM structure of a twisted-dimer transthyretin amyloid fibril from vitreous body of the eye
Summary for 7OB4
Entry DOI | 10.2210/pdb7ob4/pdb |
EMDB information | 12794 |
Descriptor | Transthyretin (1 entity in total) |
Functional Keywords | amyloid fibril, transthyretin, misfolding, protein fibril, attr amyloidosis, v30m variant, ex vivo, vitreous body |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 14 |
Total formula weight | 193331.96 |
Authors | Iakovleva, I.,Sauer-Eriksson, A.E. (deposition date: 2021-04-21, release date: 2021-12-15, Last modification date: 2022-02-16) |
Primary citation | Iakovleva, I.,Hall, M.,Oelker, M.,Sandblad, L.,Anan, I.,Sauer-Eriksson, A.E. Structural basis for transthyretin amyloid formation in vitreous body of the eye. Nat Commun, 12:7141-7141, 2021 Cited by PubMed: 34880242DOI: 10.1038/s41467-021-27481-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.22 Å) |
Structure validation
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