7OB3
hSTING in complex with 3',3'-c-di-araAMP
Summary for 7OB3
Entry DOI | 10.2210/pdb7ob3/pdb |
Descriptor | Stimulator of interferon genes protein, 3',3'-c-di-araAMP (3 entities in total) |
Functional Keywords | cdn, innate immune system, receptor, protein binding |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 23847.48 |
Authors | |
Primary citation | Novotna, B.,Hola, L.,Stas, M.,Gutten, O.,Smola, M.,Zavrel, M.,Vavrina, Z.,Budesinsky, M.,Liboska, R.,Chevrier, F.,Dobias, J.,Boura, E.,Rulisek, L.,Birkus, G. Enzymatic Synthesis of 3'-5', 3'-5' Cyclic Dinucleotides, Their Binding Properties to the Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations Biochemistry, 2021 Cited by DOI: 10.1021/acs.biochem.1c00692PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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