7OA0

Crystal structure of di-phosphorylated human CLK1 in complex with 5-(6,7-dichloro-1H-indol-3-yl)pyrimidin-4-amine

This is a non-PDB format compatible entry.

Summary for 7OA0

• Entry DOI: 10.2210/pdb7oa0/pdb
• Related: 6QTY 6R6E 6R6X 6R8D 6R8J
• Descriptor: Dual specificity protein kinase CLK1, 5-[6,7-bis(chloranyl)-1-methyl-indol-3-yl]pyrimidin-4-amine (3 entities in total)
• Functional Keywords: clk1, splicing, kinase, viral infection, signaling protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 39742.50

Authors

Livnah, O.,Domovich, Y.,Bracher, F.,Aiger, C. (deposition date: 2021-04-18, release date: 2022-05-04, Last modification date: 2024-01-31)

• Primary citation: Livnah, O.,Domovich, Y.,Bracher, F.,Aiger, C.; Development of novel CLK1 inhibitors as potential drugs for treatment of Chikungunya virus infections; To Be Published,

Experimental method