7O6R

Crystal structure of bovine Hsc70(aa1-554)E213A/D214A in complex with 1H-Indazole

Summary for 7O6R

Entry DOI	10.2210/pdb7o6r/pdb
Related	7ODB 7ODD 7ODI
Descriptor	Heat shock cognate 71 kDa protein, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 1H-indazole, ... (8 entities in total)
Functional Keywords	chaperone
Biological source	Bos taurus (Bovine)
Total number of polymer chains	1
Total formula weight	61658.84
Authors	Zehe, M.,Grimm, C.,Sotriffer, C. (deposition date: 2021-04-12, release date: 2022-05-04, Last modification date: 2024-02-14)
Primary citation	Zehe, M.,Kehrein, J.,Schollmayer, C.,Plank, C.,Kovacs, H.,Merino Asumendi, E.,Holzgrabe, U.,Grimm, C.,Sotriffer, C. Combined In-Solution Fragment Screening and Crystallographic Binding-Mode Analysis with a Two-Domain Hsp70 Construct. Acs Chem.Biol., 2024 Cited by PubMed: 38317495 DOI: 10.1021/acschembio.3c00589 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation