7O5V
Crystal structure of holo-H44A mutant of Hydroxy ketone aldolase (SwHKA) from Sphingomonas wittichii RW1, in complex with Hydroxypyruvate
This is a non-PDB format compatible entry.
Summary for 7O5V
Entry DOI | 10.2210/pdb7o5v/pdb |
Related | 6R62 7NNK 7NR1 7NUJ 7O5I 7O5R |
Descriptor | HpcH/HpaI aldolase, MAGNESIUM ION, BROMIDE ION, ... (6 entities in total) |
Functional Keywords | class ii pyruvate aldolase, metal dependent aldolase, aldol reaction, magnesium, carbon bond formation, holo, hydroxupyruvate, lyase |
Biological source | Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273) |
Total number of polymer chains | 2 |
Total formula weight | 53549.29 |
Authors | Laustsen, J.,Justo, I.,Marsden, S.R.,Hanefeld, U.,Bento, I. (deposition date: 2021-04-09, release date: 2022-11-16, Last modification date: 2024-01-31) |
Primary citation | Marsden, S.R.,Wijma, H.J.,Mohr, M.K.F.,Justo, I.,Hagedoorn, P.L.,Laustsen, J.,Jeffries, C.M.,Svergun, D.,Mestrom, L.,McMillan, D.G.G.,Bento, I.,Hanefeld, U. Substrate Induced Movement of the Metal Cofactor between Active and Resting State. Angew.Chem.Int.Ed.Engl., 61:e202213338-e202213338, 2022 Cited by PubMed: 36214476DOI: 10.1002/anie.202213338 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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