7O50

Crystal structure of human legumain in complex with Gly-Ser-Asn peptide

7O50 の概要

• エントリーDOI: 10.2210/pdb7o50/pdb
• 分子名称: Legumain, GLY-SER-ASN, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: enzyme, cysteine protease, ligase, asparaginyl endopeptidase, substrate, hydrolase
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 62209.35

構造登録者

Dall, E.,Brandstetter, H. (登録日: 2021-04-07, 公開日: 2021-09-22, 最終更新日: 2024-01-31)

• 主引用文献: Dall, E.,Stanojlovic, V.,Demir, F.,Briza, P.,Dahms, S.O.,Huesgen, P.F.,Cabrele, C.,Brandstetter, H.; The Peptide Ligase Activity of Human Legumain Depends on Fold Stabilization and Balanced Substrate Affinities.; Acs Catalysis, 11:11885-11896, 2021; PubMed: 34621593; DOI: 10.1021/acscatal.1c02057

実験手法

X-RAY DIFFRACTION (1.9 Å)