7O3B

Crystal structure of the TTBK2-CEP164 complex bound to a camelid nanobody

Summary for 7O3B

• Entry DOI: 10.2210/pdb7o3b/pdb
• Related: 7NWJ 7O06 7O0S
• Descriptor: Nanobody 36Z, Tau-tubulin kinase 2,Centrosomal protein of 164 kDa (3 entities in total)
• Functional Keywords: centriole, centrosome, basal body, ciliogenesis, structural protein
• Biological source: Camelidae mixed library; More
• Total number of polymer chains: 6
• Total formula weight: 84450.78

Authors

e Silva, I.R.,van Breugel, M. (deposition date: 2021-04-01, release date: 2021-09-15, Last modification date: 2024-01-31)

• Primary citation: Rosa E Silva, I.,Bino, L.,Johnson, C.M.,Rutherford, T.J.,Neuhaus, D.,Andreeva, A.,Cajanek, L.,van Breugel, M.; Molecular mechanisms underlying the role of the centriolar CEP164-TTBK2 complex in ciliopathies.; Structure, 30:114-128.e9, 2022; PubMed: 34499853; DOI: 10.1016/j.str.2021.08.007

Experimental method

X-RAY DIFFRACTION (2.4 Å)