7O33

Crystal structure of the anti-PAS Fab 3.1 in complex with its epitope peptide

Summary for 7O33

• Entry DOI: 10.2210/pdb7o33/pdb
• Related: 7O2Z 7O30 7O31
• Descriptor: anti-PAS Fab 3.1 chimeric light chain, anti-PAS Fab 3.1 chimeric heavy chain, APSA epitope peptide, ... (4 entities in total)
• Functional Keywords: antibody, disordered protein antigen, pas polypeptide, protein engineering, immune system
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 3
• Total formula weight: 48741.42

Authors

Schilz, J.,Skerra, A. (deposition date: 2021-04-01, release date: 2021-07-07, Last modification date: 2024-01-31)

• Primary citation: Schilz, J.,Binder, U.,Friedrich, L.,Gebauer, M.,Lutz, C.,Schlapschy, M.,Schiefner, A.,Skerra, A.; Molecular recognition of structurally disordered Pro/Ala-rich sequences (PAS) by antibodies involves an Ala residue at the hot spot of the epitope.; J.Mol.Biol., 433:167113-167113, 2021; PubMed: 34161780; DOI: 10.1016/j.jmb.2021.167113

Experimental method

X-RAY DIFFRACTION (1.85 Å)