7O31
Crystal structure of the anti-PAS Fab 1.2 in complex with its epitope peptide and the anti-Kappa VHH domain
Summary for 7O31
Entry DOI | 10.2210/pdb7o31/pdb |
Related | 7O2Z 7O30 7O31 |
Descriptor | anti-PAS Fab 1.2 chimeric light chain, anti-PAS Fab 1.2 chimeric heavy chain, anti-Kappa VHH domain, ... (6 entities in total) |
Functional Keywords | antibody, disordered protein antigen, pas polypeptide, protein engineering, immune system |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 4 |
Total formula weight | 63947.00 |
Authors | Schilz, J.,Schiefner, A.,Skerra, A. (deposition date: 2021-04-01, release date: 2021-07-07, Last modification date: 2024-01-31) |
Primary citation | Schilz, J.,Binder, U.,Friedrich, L.,Gebauer, M.,Lutz, C.,Schlapschy, M.,Schiefner, A.,Skerra, A. Molecular recognition of structurally disordered Pro/Ala-rich sequences (PAS) by antibodies involves an Ala residue at the hot spot of the epitope. J.Mol.Biol., 433:167113-167113, 2021 Cited by PubMed: 34161780DOI: 10.1016/j.jmb.2021.167113 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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