7O30
Crystal structure of the anti-PAS Fab 1.1 in complex with its epitope peptide
Summary for 7O30
Entry DOI | 10.2210/pdb7o30/pdb |
Related | 7O2Z 7O31 7O33 |
Descriptor | anti-PAS Fab 1.1 chimeric light chain, anti-PAS Fab 1.1 chimeric heavy chain, PAS#1 epitope peptide, ... (4 entities in total) |
Functional Keywords | antibody, disordered protein antigen, pas polypeptide, protein engineering, immune system |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 6 |
Total formula weight | 99128.51 |
Authors | Schilz, J.,Schiefner, A.,Skerra, A. (deposition date: 2021-04-01, release date: 2021-07-07, Last modification date: 2024-01-31) |
Primary citation | Schilz, J.,Binder, U.,Friedrich, L.,Gebauer, M.,Lutz, C.,Schlapschy, M.,Schiefner, A.,Skerra, A. Molecular recognition of structurally disordered Pro/Ala-rich sequences (PAS) by antibodies involves an Ala residue at the hot spot of the epitope. J.Mol.Biol., 433:167113-167113, 2021 Cited by PubMed: 34161780DOI: 10.1016/j.jmb.2021.167113 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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