7O2S
Crystal structure of a tetrameric form of Carbonic anhydrase from Schistosoma mansoni
Summary for 7O2S
| Entry DOI | 10.2210/pdb7o2s/pdb |
| Related | 7BM4 7NEX 7NG1 |
| Descriptor | Carbonic anhydrase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
| Functional Keywords | complex, inhibitor, lyase |
| Biological source | Schistosoma mansoni (Blood fluke) |
| Total number of polymer chains | 1 |
| Total formula weight | 38969.58 |
| Authors | Ferraroni, M.,Angeli, A. (deposition date: 2021-03-31, release date: 2022-04-13, Last modification date: 2024-01-31) |
| Primary citation | Angeli, A.,Ferraroni, M.,Da'dara, A.A.,Selleri, S.,Pinteala, M.,Carta, F.,Skelly, P.J.,Supuran, C.T. Structural Insights into Schistosoma mansoni Carbonic Anhydrase (SmCA) Inhibition by Selenoureido-Substituted Benzenesulfonamides. J.Med.Chem., 64:10418-10428, 2021 Cited by PubMed: 34232641DOI: 10.1021/acs.jmedchem.1c00840 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.28 Å) |
Structure validation
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