7O1B

Human phosphomannomutase 2 (PMM2) wild-type co-crystallized with the activator glucose 1,6-bisphosphate

7O1B の概要

• エントリーDOI: 10.2210/pdb7o1b/pdb
• 分子名称: Phosphomannomutase 2, MAGNESIUM ION, 1,6-di-O-phosphono-alpha-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: glycobiology, congenital disorders of glycosylation, phosphotransferase, phosphomutase, isomerase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 57020.45

構造登録者

Ramon-Maiques, S.,Briso-Montiano, A.,Del Cano-Ochoa, F.,Vilas, A.,Perez, B.,Rubio, V. (登録日: 2021-03-29, 公開日: 2022-02-02, 最終更新日: 2024-01-31)

• 主引用文献: Briso-Montiano, A.,Del Cano-Ochoa, F.,Vilas, A.,Velazquez-Campoy, A.,Rubio, V.,Perez, B.,Ramon-Maiques, S.; Insight on molecular pathogenesis and pharmacochaperoning potential in phosphomannomutase 2 deficiency, provided by novel human phosphomannomutase 2 structures.; J Inherit Metab Dis, 45:318-333, 2022; PubMed: 34859900; DOI: 10.1002/jimd.12461

実験手法

X-RAY DIFFRACTION (3.08 Å)