7NXE

Structure of the Phospholipase C gamma 1 tSH2 domain in complex with a phosphorylated KSHV pK15 peptide

7NXE の概要

• エントリーDOI: 10.2210/pdb7nxe/pdb
• 分子名称: Isoform 2 of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, Protein K15 (3 entities in total)
• 機能のキーワード: kshv, complex, phosphorylation, viral protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 29751.14

構造登録者

Ssebyatika, G.,Krey, T. (登録日: 2021-03-18, 公開日: 2021-06-09, 最終更新日: 2024-01-31)

• 主引用文献: Samarina, N.,Ssebyatika, G.,Tikla, T.,Waldmann, J.Y.,Abere, B.,Nanna, V.,Marasco, M.,Carlomagno, T.,Krey, T.,Schulz, T.F.; Recruitment of phospholipase C gamma 1 to the non-structural membrane protein pK15 of Kaposi Sarcoma-associated herpesvirus promotes its Src-dependent phosphorylation.; Plos Pathog., 17:e1009635-e1009635, 2021; PubMed: 34143834; DOI: 10.1371/journal.ppat.1009635

実験手法

X-RAY DIFFRACTION (2.1 Å)