7NWT

Initiated 70S ribosome in complex with 2A protein from encephalomyocarditis virus (EMCV)

This is a non-PDB format compatible entry.

Summary for 7NWT

• Entry DOI: 10.2210/pdb7nwt/pdb
• Related: 7BNY
• EMDB information: 12635
• Descriptor: 50S ribosomal protein L2, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (61 entities in total)
• Functional Keywords: 70s ribosome, initiation complex, emcv, cardiovirus, 2a, picornavirus, frameshifting, prf, rna-binding protein, protein-mediated frameshifting, ribosome-binding protein, beta-shell, viral protein, ribosome
• Biological source: Mengo encephalomyocarditis virus; More
• Total number of polymer chains: 59
• Total formula weight: 2297585.21

Authors

Hill, C.H.,Napthine, S.,Pekarek, L.,Kibe, A.,Firth, A.E.,Graham, S.C.,Caliskan, N.,Brierley, I. (deposition date: 2021-03-17, release date: 2021-12-15, Last modification date: 2024-04-24)

• Primary citation: Hill, C.H.,Pekarek, L.,Napthine, S.,Kibe, A.,Firth, A.E.,Graham, S.C.,Caliskan, N.,Brierley, I.; Structural and molecular basis for Cardiovirus 2A protein as a viral gene expression switch; Nat Commun, 12:7166-, 2021; DOI: 10.1038/s41467-021-27400-7

Experimental method

ELECTRON MICROSCOPY (2.66 Å)