7NT3

Crystal structure of SARS CoV2 main protease in complex with FSCU015

7NT3 の概要

• エントリーDOI: 10.2210/pdb7nt3/pdb
• 分子名称: 3C-like proteinase, DIMETHYL SULFOXIDE, ~{N}-[(1~{S})-2-(1,3-benzodioxol-5-ylmethylamino)-1-(3-hydroxyphenyl)-2-oxidanylidene-ethyl]-~{N}-propyl-prop-2-enamide, ... (4 entities in total)
• 機能のキーワード: protease, complex, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 68360.06

構造登録者

Oerlemans, R.,Eris, D.,Wang, M.,Sharpe, M.,Domling, A.,Groves, M.R. (登録日: 2021-03-08, 公開日: 2021-06-16, 最終更新日: 2024-01-31)

• 主引用文献: Sutanto, F.,Shaabani, S.,Oerlemans, R.,Eris, D.,Patil, P.,Hadian, M.,Wang, M.,Sharpe, M.E.,Groves, M.R.,Domling, A.; Combining High-Throughput Synthesis and High-Throughput Protein Crystallography for Accelerated Hit Identification.; Angew.Chem.Int.Ed.Engl., 60:18231-18239, 2021; PubMed: 34097796; DOI: 10.1002/anie.202105584

実験手法

X-RAY DIFFRACTION (2.325 Å)