7NRE
Crystal structure of E.coli BamA beta-barrel in complex with darobactin (crystal form 1)
Summary for 7NRE
Entry DOI | 10.2210/pdb7nre/pdb |
Related PRD ID | PRD_002330 |
Descriptor | Outer membrane protein assembly factor BamA, Darobactin, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, ... (5 entities in total) |
Functional Keywords | beta-barrel, outer membrane, protein insertion, protein folding, protein maturation, antibiotic, natural product, cyclized peptide, membrane protein |
Biological source | Escherichia coli O157:H7 More |
Total number of polymer chains | 2 |
Total formula weight | 48268.20 |
Authors | Jakob, R.P.,Kaur, H.,Marzinek, J.K.,Green, R.,Imai, Y.,Bolla, J.,Robinson, C.,Bond, P.J.,Lewis, K.,Maier, T.,Hiller, S. (deposition date: 2021-03-03, release date: 2021-04-21, Last modification date: 2024-01-31) |
Primary citation | Kaur, H.,Jakob, R.P.,Marzinek, J.K.,Green, R.,Imai, Y.,Bolla, J.R.,Agustoni, E.,Robinson, C.V.,Bond, P.J.,Lewis, K.,Maier, T.,Hiller, S. The antibiotic darobactin mimics a beta-strand to inhibit outer membrane insertase. Nature, 593:125-129, 2021 Cited by PubMed: 33854236DOI: 10.1038/s41586-021-03455-w PDB entries with the same primary citation |
Experimental method |
Structure validation
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