7NR6
Structure of NUDT15 in complex with NSC56456
Summary for 7NR6
Entry DOI | 10.2210/pdb7nr6/pdb |
Descriptor | Probable 8-oxo-dGTP diphosphatase NUDT15, 1,2-ETHANEDIOL, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | inhibitor, complex, nucleoside triphosphate pyrophosphohydrolase, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 37941.42 |
Authors | Rehling, D.,Stenmark, P. (deposition date: 2021-03-03, release date: 2022-03-23, Last modification date: 2024-01-31) |
Primary citation | Valerie, N.C.K.,Rehling, D.,Stenmark, P. Coupling cellular target engagement to drug-induced responses with CeTEAM To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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