7NR1

Crystal structure of holo-S116A mutant of Hydroxy ketone aldolase (SwHKA) from Sphingomonas wittichii RW1

Summary for 7NR1

Entry DOI	10.2210/pdb7nr1/pdb
Related	6R62 7NNK
Descriptor	HpcH/HpaI aldolase, MAGNESIUM ION (3 entities in total)
Functional Keywords	class ii pyruvate aldolase, metal dependent aldolase, aldol reaction, magnesium, carbon bond formation, lyase
Biological source	Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)
Total number of polymer chains	2
Total formula weight	53285.06
Authors	Justo, I.,Marsden, S.R.,Hanefeld, U.,Bento, I. (deposition date: 2021-03-02, release date: 2022-09-21, Last modification date: 2024-01-31)
Primary citation	Marsden, S.R.,Wijma, H.J.,Mohr, M.K.F.,Justo, I.,Hagedoorn, P.L.,Laustsen, J.,Jeffries, C.M.,Svergun, D.,Mestrom, L.,McMillan, D.G.G.,Bento, I.,Hanefeld, U. Substrate Induced Movement of the Metal Cofactor between Active and Resting State. Angew.Chem.Int.Ed.Engl., 61:e202213338-e202213338, 2022 Cited by PubMed: 36214476 DOI: 10.1002/anie.202213338 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation