7NPJ
Crystal structure of Mycobacterium tuberculosis ArgC in complex with 6-phenoxy-3-pyridinamine
Summary for 7NPJ
Entry DOI | 10.2210/pdb7npj/pdb |
Descriptor | N-acetyl-gamma-glutamyl-phosphate reductase, 6-phenoxy-3-pyridinamine (2 entities in total) |
Functional Keywords | argc, n-acetyl-gamma-glutamyl-phosphate reductase, nagpr, arginine biosynthesis, oxidoreductase |
Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Total number of polymer chains | 8 |
Total formula weight | 292068.65 |
Authors | Gupta, P.,Mendes, V.,Blundell, T.L. (deposition date: 2021-02-27, release date: 2021-06-30, Last modification date: 2024-01-31) |
Primary citation | Gupta, P.,Thomas, S.E.,Zaidan, S.A.,Pasillas, M.A.,Cory-Wright, J.,Sebastian-Perez, V.,Burgess, A.,Cattermole, E.,Meghir, C.,Abell, C.,Coyne, A.G.,Jacobs, W.R.,Blundell, T.L.,Tiwari, S.,Mendes, V. A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis Comput Struct Biotechnol J, 19:3491-3506, 2021 Cited by DOI: 10.1016/j.csbj.2021.06.006PDB entries with the same primary citation |
Experimental method |
Structure validation
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