7NL0
Cryo-EM structure of the Lin28B nucleosome core particle
Summary for 7NL0
Entry DOI | 10.2210/pdb7nl0/pdb |
EMDB information | 12453 |
Descriptor | Histone H3.1, Histone H4, Histone H2A type 1-B/E, ... (6 entities in total) |
Functional Keywords | reprogramming, oct4 binding sites, nucleosome, gene regulation |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 10 |
Total formula weight | 209858.79 |
Authors | Roberts, G.A.,Ozkan, B.,Gachulincova, I.,O Dwyer, M.R.,Hall-Ponsele, E.,Saxena, M.,Robinson, P.J.,Soufi, A. (deposition date: 2021-02-19, release date: 2021-08-11, Last modification date: 2024-07-10) |
Primary citation | Roberts, G.A.,Ozkan, B.,Gachulincova, I.,O'Dwyer, M.R.,Hall-Ponsele, E.,Saxena, M.,Robinson, P.J.,Soufi, A. Dissecting OCT4 defines the role of nucleosome binding in pluripotency. Nat.Cell Biol., 23:834-845, 2021 Cited by PubMed: 34354236DOI: 10.1038/s41556-021-00727-5 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.5 Å) |
Structure validation
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