7NKU

diazaborine bound Drg1(AFG2)

Summary for 7NKU

• Entry DOI: 10.2210/pdb7nku/pdb
• EMDB information: 12448
• Descriptor: ATPase family gene 2 protein, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, 6-METHYL-2(PROPANE-1-SULFONYL)-2H-THIENO[3,2-D][1,2,3]DIAZABORININ-1-OL (3 entities in total)
• Functional Keywords: drg1, afg2, ribosome maturation, aaa protein, diazaborine, inhibitor, ribosome
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
• Total number of polymer chains: 6
• Total formula weight: 517016.19

Authors

Prattes, M.,Bergler, H.,Haselbach, D. (deposition date: 2021-02-19, release date: 2021-06-23)

• Primary citation: Prattes, M.,Grishkovskaya, I.,Hodirnau, V.V.,Rossler, I.,Klein, I.,Hetzmannseder, C.,Zisser, G.,Gruber, C.C.,Gruber, K.,Haselbach, D.,Bergler, H.; Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine.; Nat Commun, 12:3483-3483, 2021; PubMed: 34108481; DOI: 10.1038/s41467-021-23854-x

Experimental method

ELECTRON MICROSCOPY (3.4 Å)