7NIU
Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab and QA2-Fab (apo-inward-open conformation)
Summary for 7NIU
Entry DOI | 10.2210/pdb7niu/pdb |
EMDB information | 12365 |
Descriptor | Isoform 2 of Phosphatidylcholine translocator ABCB4, QA2 Fab-fragment light chain, QA2 Fab-fragment heavy chain, ... (6 entities in total) |
Functional Keywords | abcb4, mdr3, nanodisc, lipid transporter, transporter, phosphatidylcholine, protein transport |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 5 |
Total formula weight | 238786.66 |
Authors | |
Primary citation | Nosol, K.,Bang-Sorensen, R.,Irobalieva, R.N.,Erramilli, S.K.,Stieger, B.,Kossiakoff, A.A.,Locher, K.P. Structures of ABCB4 provide insight into phosphatidylcholine translocation. Proc.Natl.Acad.Sci.USA, 118:-, 2021 Cited by PubMed: 34385322DOI: 10.1073/pnas.2106702118 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.2 Å) |
Structure validation
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