7NIU

Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab and QA2-Fab (apo-inward-open conformation)

Summary for 7NIU

• Entry DOI: 10.2210/pdb7niu/pdb
• EMDB information: 12365
• Descriptor: Isoform 2 of Phosphatidylcholine translocator ABCB4, QA2 Fab-fragment light chain, QA2 Fab-fragment heavy chain, ... (6 entities in total)
• Functional Keywords: abcb4, mdr3, nanodisc, lipid transporter, transporter, phosphatidylcholine, protein transport
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 238786.66

Authors

Nosol, K.,Locher, K.P. (deposition date: 2021-02-14, release date: 2021-08-25)

• Primary citation: Nosol, K.,Bang-Sorensen, R.,Irobalieva, R.N.,Erramilli, S.K.,Stieger, B.,Kossiakoff, A.A.,Locher, K.P.; Structures of ABCB4 provide insight into phosphatidylcholine translocation.; Proc.Natl.Acad.Sci.USA, 118:-, 2021; PubMed: 34385322; DOI: 10.1073/pnas.2106702118

Experimental method

ELECTRON MICROSCOPY (4.2 Å)