7NDV

X-ray structure of acetylcholine-binding protein (AChBP) in complex with FL001888.

7NDV の概要

• エントリーDOI: 10.2210/pdb7ndv/pdb
• 分子名称: Acetylcholine-binding protein, 4-[4-(trifluoromethyl)phenoxy]piperidine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: fragment based drug design, acetylcholine-binding protein, choline-binding protein
• 由来する生物種: Lymnaea stagnalis (Great pond snail, Helix stagnalis)
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 274300.66

構造登録者

Cederfelt, D.,Boronat, P.,Dobritzsch, D.,Hennig, S.,Fitzgerald, E.A.,de Esch, I.J.P.,Danielson, U.H. (登録日: 2021-02-02, 公開日: 2021-04-07, 最終更新日: 2024-01-31)

• 主引用文献: Fitzgerald, E.A.,Butko, M.T.,Boronat, P.,Cederfelt, D.,Abramsson, M.,Ludviksdottir, H.,van Muijlwijk-Koezen, J.,de Esch, I.J.P.,Dobritzsch, D.,Young, T.,Danielson, U.H.; Discovery of fragments inducing conformational effects in dynamic proteins using a second-harmonic generation biosensor; RSC Advances, 11:7527-7537, 2021

実験手法

X-RAY DIFFRACTION (1.7 Å)