7NB9

E. coli NfsA with nitrofurantoin

7NB9 の概要

• エントリーDOI: 10.2210/pdb7nb9/pdb
• 分子名称: Oxygen-insensitive NADPH nitroreductase, FLAVIN MONONUCLEOTIDE, 1-[(~{E})-(5-nitrofuran-2-yl)methylideneamino]imidazolidine-2,4-dione, ... (5 entities in total)
• 機能のキーワード: complex with antibiotic substrate, flavoprotein, nitroreductase, oxidoreductase
• 由来する生物種: Escherichia coli (strain K12)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 27605.30

構造登録者

Day, M.D.,Jarrom, D.,Grainger, A.I.,Parr, R.J.,Hyde, E.I.,White, S.A. (登録日: 2021-01-25, 公開日: 2021-07-21, 最終更新日: 2024-01-31)

• 主引用文献: Day, M.A.,Jarrom, D.,Christofferson, A.J.,Graziano, A.E.,Anderson, J.L.R.,Searle, P.F.,Hyde, E.I.,White, S.A.; The structures of E. coli NfsA bound to the antibiotic nitrofurantoin; to 1,4-benzoquinone and to FMN.; Biochem.J., 478:2601-2617, 2021; PubMed: 34142705; DOI: 10.1042/BCJ20210160

実験手法

X-RAY DIFFRACTION (1.09 Å)