7NB5

Structure of EstD11 S144A in complex with naproxen p-nitrophenol ester

Summary for 7NB5

Entry DOI	10.2210/pdb7nb5/pdb
Related	7AT0 7AT2 7AT3 7AT4 7ATD 7ATF 7ATQ 7AUY 7AV5
Descriptor	EstD11 S144A, (4-nitrophenyl) (2~{S})-2-(6-methoxynaphthalen-2-yl)propanoate (3 entities in total)
Functional Keywords	esterase hormone-sensitive lipase metagenome library crystal structure, hydrolase
Biological source	uncultured bacterium
Total number of polymer chains	1
Total formula weight	32392.18
Authors	Miguel-Ruano, V.,Rivera, I.,Hermoso, J.A. (deposition date: 2021-01-25, release date: 2021-03-03, Last modification date: 2024-01-31)
Primary citation	Miguel-Ruano, V.,Rivera, I.,Rajkovic, J.,Knapik, K.,Torrado, A.,Otero, J.M.,Beneventi, E.,Becerra, M.,Sanchez-Costa, M.,Hidalgo, A.,Berenguer, J.,Gonzalez-Siso, M.I.,Cruces, J.,Rua, M.L.,Hermoso, J.A. Biochemical and Structural Characterization of a novel thermophilic esterase EstD11 provide catalytic insights for the HSL family. Comput Struct Biotechnol J, 19:1214-1232, 2021 Cited by PubMed: 33680362 DOI: 10.1016/j.csbj.2021.01.047 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.13 Å)

Structure validation