7N9B

Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes-CovS with NB21

Summary for 7N9B

• Entry DOI: 10.2210/pdb7n9b/pdb
• EMDB information: 24255
• Descriptor: Spike glycoprotein, NB21 Nanobody (2 entities in total)
• Functional Keywords: covs nb21 nanobody, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2, COVID-19 virus); More
• Total number of polymer chains: 5
• Total formula weight: 488479.40

Authors

Sun, D.,Zhang, C.,Shi, Y. (deposition date: 2021-06-17, release date: 2021-08-04, Last modification date: 2024-10-09)

• Primary citation: Sun, D.,Sang, Z.,Kim, Y.J.,Xiang, Y.,Cohen, T.,Belford, A.K.,Huet, A.,Conway, J.F.,Sun, J.,Taylor, D.J.,Schneidman-Duhovny, D.,Zhang, C.,Huang, W.,Shi, Y.; Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes; Nat Commun, 12:4676-, 2021; DOI: 10.1038/s41467-021-24963-3

Experimental method

ELECTRON MICROSCOPY (3.8 Å)