7N9B

Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes-CovS with NB21

7N9B の概要

• エントリーDOI: 10.2210/pdb7n9b/pdb
• EMDBエントリー: 24255
• 分子名称: Spike glycoprotein, NB21 Nanobody (2 entities in total)
• 機能のキーワード: covs nb21 nanobody, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2, COVID-19 virus); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 488479.40

構造登録者

Sun, D.,Zhang, C.,Shi, Y. (登録日: 2021-06-17, 公開日: 2021-08-04, 最終更新日: 2024-10-09)

• 主引用文献: Sun, D.,Sang, Z.,Kim, Y.J.,Xiang, Y.,Cohen, T.,Belford, A.K.,Huet, A.,Conway, J.F.,Sun, J.,Taylor, D.J.,Schneidman-Duhovny, D.,Zhang, C.,Huang, W.,Shi, Y.; Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes; Nat Commun, 12:4676-, 2021; DOI: 10.1038/s41467-021-24963-3

実験手法

ELECTRON MICROSCOPY (3.8 Å)