7N6W

Structure of uncleaved HIV-1 JR-FL Env glycoprotein trimer in state U2 bound to small Molecule HIV-1 Entry Inhibitor BMS-378806

7N6W の概要

• エントリーDOI: 10.2210/pdb7n6w/pdb
• EMDBエントリー: 23861
• 分子名称: Envelope glycoprotein gp160, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: hiv-1, envelope, virus, glycoprotein, viral protein
• 由来する生物種: Human immunodeficiency virus 1
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 314559.69

構造登録者

Zhang, S.,Wang, K.,Mao, Y. (登録日: 2021-06-09, 公開日: 2021-09-22, 最終更新日: 2021-12-08)

• 主引用文献: Zhang, S.,Wang, K.,Wang, W.L.,Nguyen, H.T.,Chen, S.,Lu, M.,Go, E.P.,Ding, H.,Steinbock, R.T.,Desaire, H.,Kappes, J.C.,Sodroski, J.,Mao, Y.; Asymmetric Structures and Conformational Plasticity of the Uncleaved Full-Length Human Immunodeficiency Virus Envelope Glycoprotein Trimer.; J.Virol., 95:e0052921-e0052921, 2021; PubMed: 34549974; DOI: 10.1128/JVI.00529-21

実験手法

ELECTRON MICROSCOPY (4.7 Å)