7N6P
Crystal structure of the anti-EBOV and SUDV monoclonal antibody 1C3 Fab
Summary for 7N6P
Entry DOI | 10.2210/pdb7n6p/pdb |
Descriptor | 1C3 Fab heavy chain, 1C3 Fab light chain (3 entities in total) |
Functional Keywords | glycoprotein, immune system, antibody |
Biological source | Homo sapiens More |
Total number of polymer chains | 4 |
Total formula weight | 95426.70 |
Authors | Milligan, J.C.,Yu, X.,Buck, T.,Saphire, E.O. (deposition date: 2021-06-08, release date: 2022-04-06) |
Primary citation | Milligan, J.C.,Davis, C.W.,Yu, X.,Ilinykh, P.A.,Huang, K.,Halfmann, P.J.,Cross, R.W.,Borisevich, V.,Agans, K.N.,Geisbert, J.B.,Chennareddy, C.,Goff, A.J.,Piper, A.E.,Hui, S.,Shaffer, K.C.L.,Buck, T.,Heinrich, M.L.,Branco, L.M.,Crozier, I.,Holbrook, M.R.,Kuhn, J.H.,Kawaoka, Y.,Glass, P.J.,Bukreyev, A.,Geisbert, T.W.,Worwa, G.,Ahmed, R.,Saphire, E.O. Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses. Cell, 185:995-1007.e18, 2022 Cited by PubMed: 35303429DOI: 10.1016/j.cell.2022.02.023 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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